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118414-59-8

118414-59-8 structure
118414-59-8 structure
  • Name: nTZDpa
  • Chemical Name: 5-chloro-1-[(4-chlorophenyl)methyl]-3-phenylsulfanylindole-2-carboxylic acid
  • CAS Number: 118414-59-8
  • Molecular Formula: C22H15Cl2NO2S
  • Molecular Weight: 428.33
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2016-03-16 22:35:48
  • Modify Date: 2024-01-02 21:30:50
  • nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption[1].

Name 5-chloro-1-[(4-chlorophenyl)methyl]-3-phenylsulfanylindole-2-carboxylic acid
Synonyms nTzDpa
NZA
Description nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption[1].
Related Catalog
References

[1]. Kim W, et al. Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters. ACS Infect Dis. 2018 Nov 9;4(11):1540-1545.  

Density 1.37g/cm3
Boiling Point 628.9ºC at 760mmHg
Molecular Formula C22H15Cl2NO2S
Molecular Weight 428.33
Flash Point 334.2ºC
Exact Mass 427.02000
PSA 67.53000
LogP 6.84580
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.672
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
RIDADR UN 2811 6.1 / PGIII