118414-59-8

118414-59-8 structure

Name: nTZDpa
Chemical Name: 5-chloro-1-[(4-chlorophenyl)methyl]-3-phenylsulfanylindole-2-carboxylic acid
CAS Number: 118414-59-8
Molecular Formula: C₂₂H₁₅Cl₂NO₂S
Molecular Weight: 428.33
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-03-16 22:35:48
Modify Date: 2025-08-26 19:15:09
nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption[1].

Name	5-chloro-1-[(4-chlorophenyl)methyl]-3-phenylsulfanylindole-2-carboxylic acid
Synonyms	nTzDpa NZA

Description	nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Kim W, et al. Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters. ACS Infect Dis. 2018 Nov 9;4(11):1540-1545.