88-14-2

88-14-2 structure

Name: Furan-2-carboxylic acid
Chemical Name: 2-furoic acid
CAS Number: 88-14-2
Molecular Formula: C₅H₄O₃
Molecular Weight: 112.084
Catalog: Biochemical Amino acids and their derivatives Glycine derivatives
Create Date: 2018-06-23 18:20:39
Modify Date: 2024-01-02 15:22:08
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].

Name	2-furoic acid
Synonyms	2-furanyl-carboxylic acid pyromucic acid Furan-2-carboxylic acid 2-FURANCARBONYL CHLORIDE 2-Furoic acid a-Furoicacid Kyselina 2-furoova 2- FUROIC ACID 2-FUROIC ACID/FURAN-2-CARBOXYLIC ACID Furoica 2-FURANCARBOXYLICACID α-Furoic acid EINECS 208-422-9 2-Furanoic acid 2-Furancarboxylic acid MFCD00003228 2-furan-carboxylic acid a-Furoic Acid

Description	2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Acyltransferase Signaling Pathways >> Metabolic Enzyme/Protease >> ATP Citrate Lyase Research Areas >> Metabolic Disease
In Vivo	2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels[2]. 2-Furoic acid also lowers the liver and small intestine ATP dependent citrate lyase, acetyl CoA synthetase, acyl CoA cholesterol acyl transferase, sn-glycerol 3-phosphate acyl transferase, phosphatidylate phosphohydrolase and heparin induced lipoprotein lipase activities[2]. 2-Furoic acid shows the LD50 of 250 mg/kg i.p. in the acute toxicity studies in mice[2].
References	[1]. Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199. [2]. Hall IH, et al. The hypolipidemic effects of 2-furoic acid in Sprague-Dawley rats. Arch Pharm (Weinheim). 1993 Jan;326(1):15-23.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 1,15,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1977 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 774 (estimated) No. of Female Employees: 10 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	C;Xi
Risk Phrases	R34;R36/37/38
Safety Phrases	S26-S36/37/39-S45-S36
RIDADR	UN 3265 8/PG 2
WGK Germany	3
RTECS	LV1763000
HS Code	29321900

HS Code	2932190090
Summary	2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%