DC Chemicals Limited
China
Product Name: Akt-I-1
Price: $750.0/100mg $1200.0/250mg $2600.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: AKT-L-1
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

473382-39-7

473382-39-7 structure

473382-39-7 structure

Name: Akt-l-1
Chemical Name: N-(7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N',N',2,2-tetramethylpropane-1,3-diamine
CAS Number: 473382-39-7
Molecular Formula: C₂₂H₃₀N₆
Molecular Weight: 378.514
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2018-12-04 06:00:27
Modify Date: 2024-01-31 18:50:41
AKT-I-1 is a selective inhibitor of Akt1, with an IC50 of 4.6 µM[1].

Name	N-(7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N',N',2,2-tetramethylpropane-1,3-diamine
Synonyms	1,3-Propanediamine, N-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N,N,2,2-tetramethyl- Akt-l-1 N'-(7-Cyclobutyl-3-phenyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N,N,2,2-tetramethyl-1,3-propanediamine

Description	AKT-I-1 is a selective inhibitor of Akt1, with an IC50 of 4.6 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Target	Akt1:4.6 μM (IC50) Akt2:>250 μM (IC50) Akt3:>250 μM (IC50)
References	[1]. Barnett SF, et al. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors. Biochem J. 2005 Jan 15;385(Pt 2):399-408.

Density	1.2±0.1 g/cm3
Molecular Formula	C₂₂H₃₀N₆
Molecular Weight	378.514
Exact Mass	378.253204
PSA	61.58000
LogP	4.01
Index of Refraction	1.642

Precursor 2
233278-53-0 53369-71-4
DownStream 0