473382-39-7
473382-39-7 structure
- Name: Akt-l-1
- Chemical Name: N-(7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N',N',2,2-tetramethylpropane-1,3-diamine
- CAS Number: 473382-39-7
- Molecular Formula: C22H30N6
- Molecular Weight: 378.514
- Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
- Create Date: 2018-12-04 06:00:27
- Modify Date: 2025-09-13 17:34:22
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AKT-I-1 is a selective inhibitor of Akt1, with an IC50 of 4.6 µM[1].
| Name | N-(7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N',N',2,2-tetramethylpropane-1,3-diamine |
|---|---|
| Synonyms |
1,3-Propanediamine, N-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N,N,2,2-tetramethyl-
Akt-l-1 N'-(7-Cyclobutyl-3-phenyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-N,N,2,2-tetramethyl-1,3-propanediamine |
| Description | AKT-I-1 is a selective inhibitor of Akt1, with an IC50 of 4.6 µM[1]. |
|---|---|
| Related Catalog | |
| Target |
Akt1:4.6 μM (IC50) Akt2:>250 μM (IC50) Akt3:>250 μM (IC50) |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C22H30N6 |
| Molecular Weight | 378.514 |
| Exact Mass | 378.253204 |
| PSA | 61.58000 |
| LogP | 4.01 |
| Index of Refraction | 1.642 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
![6-Chloro-7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazine structure](https://image.chemsrc.com/caspic/013/233278-53-0.png)
