DC Chemicals Limited
China
Product Name: Benurestat
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzamide,4-chloro-N-[2-(hydroxyamino)-2-oxoethyl]-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

38274-54-3

38274-54-3 structure

38274-54-3 structure

Name: Benurestat
Chemical Name: 4-chloro-N-[2-(hydroxyamino)-2-oxoethyl]benzamide
CAS Number: 38274-54-3
Molecular Formula: C₉H₉ClN₂O₃
Molecular Weight: 228.63200
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-09-14 10:58:02
Modify Date: 2024-01-03 10:42:44
Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research[1].

Name	4-chloro-N-[2-(hydroxyamino)-2-oxoethyl]benzamide
Synonyms	EU-2826 Benurstat Benurestat

Description	Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vivo	Benurestat administration, 25 mg/kg, 50 mg/kg, or 100 mg/kg, causes a decrease in the urinary excretion of ammonia from rats with experimental P. mirabilis genitourinary tract infection[1]. The number of viable bacteria present in the bladders of infected rats is significantly less after the administration of Benurestat plus Nitrofurantoin, Sulfamethoxazole, or Ampicillin than the respective numbers that are obtained from control infected rats or from rats administered either component of the combination separately[1].
References	[1]. J A Andersen. Benurestat, a urease inhibitor for the therapy of infected ureolysis. Invest Urol. 1975 Mar;12(5):381-6.

Density	1.414g/cm3
Molecular Formula	C₉H₉ClN₂O₃
Molecular Weight	228.63200
Exact Mass	228.03000
PSA	78.43000
LogP	1.35700
Index of Refraction	1.59

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AK8317000

CHEMICAL NAME :: Acetohydroxamic acid, 2-(p-chlorobenzamido)-

CAS REGISTRY NUMBER :: 38274-54-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H9-Cl-N2-O3

MOLECULAR WEIGHT :: 228.65

WISWESSER LINE NOTATION :: QMV1MVR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 10 umol/disc

REFERENCE :: JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 3,557,1980

Hazard Codes	Xi
HS Code	2924299090

39735-52-9 structure

39735-52-9

~%

38274-54-3 structure

38274-54-3

Literature: Munakata; Tanaka; Toyoshima Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051

122-01-0 structure

122-01-0

~%

38274-54-3 structure

38274-54-3

Literature: Munakata; Tanaka; Toyoshima Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051

74-11-3 structure

74-11-3

~%

38274-54-3 structure

38274-54-3

Literature: Munakata; Tanaka; Toyoshima Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 7 p. 2045 - 2051

Precursor 3
39735-52-9 122-01-0 74-11-3
DownStream 0

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%