| Name | N-Succinimidyl 3-maleimidopropionate |
|---|---|
| Synonyms |
1-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl}-1H-pyrrole-2,5-dione
(2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate 1-{3-[(2,5-Dioxopyrrolidin-1-yl)oxy]-3-oxopropyl}-1H-pyrrole-2,5-dione MFCD00043141 1H-pyrrole-2,5-dione, 1-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]- |
| Description | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Noncleavable |
| Density | 1.55g/cm3 |
|---|---|
| Boiling Point | 448.8ºC at 760mmHg |
| Melting Point | 168-170 °C(lit.) |
| Molecular Formula | C11H10N2O6 |
| Molecular Weight | 266.20700 |
| Flash Point | 225.2ºC |
| Exact Mass | 266.05400 |
| PSA | 101.06000 |
| Index of Refraction | 1.605 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H335 |
| Precautionary Statements | P261 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R37 |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
|
~80%
55750-62-4 |
| Literature: CYTOS BIOTECHNOLOGY AG; WOOD, Andrew; SMITH, Helen, Kathryn; WILMSHURST, Martin, Philip; VAN, Son Thanh Patent: WO2011/23680 A2, 2011 ; Location in patent: Page/Page column 13-14 ; |
|
~%
55750-62-4 |
| Literature: Tetrahedron Letters, , vol. 39, # 11 p. 1321 - 1324 |
|
~%
55750-62-4 |
| Literature: US2012/93840 A1, ; |
|
~66%
55750-62-4 |
| Literature: Paterson, Michael J.; Eggleston, Ian M. Synthetic Communications, 2008 , vol. 38, # 2 p. 303 - 308 |
|
~%
55750-62-4 |
| Literature: Song, Hong Y.; Ngai, Mun H.; Song, Zhen Y.; MacAry, Paul A.; Hobley, Jonathan; Lear, Martin J. Organic and Biomolecular Chemistry, 2009 , vol. 7, # 17 p. 3400 - 3406 |
|
~48%
55750-62-4 |
| Literature: Augustin, Manfred; Mueller, Wolfgang Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798 |
|
~%
55750-62-4 |
| Literature: Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6400 - 6407 |
| Precursor 10 | |
|---|---|
| DownStream 1 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |