| Name | 3-Maleimidopropionic Acid |
|---|---|
| Synonyms |
BMPA
β-Maleimidopropionic acid MFCD00043030 3-(2,5-dioxopyrrol-1-yl)propanoic acid 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo- 3-Maleimidopropionic acid 3-Maleimidopropionicacid |
| Description | 3-Maleimidopropionic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 382.5±25.0 °C at 760 mmHg |
| Melting Point | 103-106 °C(lit.) |
| Molecular Formula | C7H7NO4 |
| Molecular Weight | 169.135 |
| Flash Point | 185.1±23.2 °C |
| Exact Mass | 169.037506 |
| PSA | 74.68000 |
| LogP | 0.04 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.565 |
| Storage condition | -15°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
| Precursor 4 | |
|---|---|
| DownStream 4 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |