Name | N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate |
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Synonyms | (2,5-dioxopyrrolidin-1-yl) 6-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]hexanoate |
Description | SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C17H21N3O7 |
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Molecular Weight | 379.36500 |
Exact Mass | 379.13800 |
PSA | 130.16000 |
Precursor 2 | |
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DownStream 0 |