| Name | 8-hydroxy-2'-deoxyguanosine |
|---|---|
| Synonyms |
2'-deoxy-7,8-dihydro-8-oxo-guanosine
MFCD00210311 2'-Deoxy-8-oxo-7,8-dihydroguanosine 7,8-Dihydro-8-oxo-2'-deoxyguanosine 2'-Deoxy-8-oxoguanosine 8-Oxo-7,8-dihydrodeoxyguanosine 2'-Deoxy-8-oxo-D-guanosine 8-Oxodeoxyguanosine guanosine, 2'-deoxy-8-oxo- 2'-Deoxy-8-hydroxyguanosine 8-oxo-7,8-dihydro-2'-deoxiguanosine Guanosine, 2'-deoxy-8-hydroxy- 8-oxo-7-hydrodeoxyguanosine 8-hydroxydeoxyguanosine 8-HYDROXY-2'-DEOXYGUANOSINE 8-Hydroxy-2’-deoxyguanosine 8-oxo-7,8-dihydro-2'-deoxyguanosine 2'-Deoxy-7,8-dihydro-8-oxoguanosine |
| Description | 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases. The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons[1]. |
| References |
| Density | 2.3±0.1 g/cm3 |
|---|---|
| Melting Point | 217-220ºC |
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.241 |
| Exact Mass | 283.091675 |
| PSA | 159.51000 |
| LogP | -1.32 |
| Index of Refraction | 1.955 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | MF8782675 |
| HS Code | 2934999090 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |