28585-51-5
28585-51-5 structure
- Name: 2-Thiothymidine
- Chemical Name: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one
- CAS Number: 28585-51-5
- Molecular Formula: C10H14N2O4S
- Molecular Weight: 258.29
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2018-07-15 16:17:55
- Modify Date: 2025-08-25 11:52:20
-
2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one |
|---|---|
| Synonyms |
Thymidine,2-thio
2-Thiothymidin 2-thiothymidine 2-Thio-desoxythymidin |
| Description | 2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.52 g/cm3 |
|---|---|
| Molecular Formula | C10H14N2O4S |
| Molecular Weight | 258.29 |
| Exact Mass | 258.06700 |
| PSA | 119.57000 |
| Index of Refraction | 1.672 |
|
~%
28585-51-5 |
| Literature: Hatano, Akihiko; Kurosu, Masayuki; Yonaha, Susumu; Okada, Munehiro; Uehara, Sanae Organic and Biomolecular Chemistry, 2013 , vol. 11, # 40 p. 6900 - 6905 |
|
~59%
28585-51-5 |
| Literature: Hatano, Akihiko; Harano, Aiko; Kirihara, Masayuki Chemistry Letters, 2006 , vol. 35, # 2 p. 232 - 233 |
