65-71-4

65-71-4 structure

Name: Thymine
Chemical Name: Thymine
CAS Number: 65-71-4
Molecular Formula: C₅H₆N₂O₂
Molecular Weight: 126.113
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Urinary (urea)pyrimidine
Create Date: 2018-06-12 18:01:15
Modify Date: 2025-08-20 19:04:18
Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

Name	Thymine
Synonyms	5-Methyl-2,4(1H,3H)-pyrimidinedione Clospirazine 5-methylpyrimidine-2,4-dione 5-Methyluracil THYMINE extrapure Thymine 4-Hydroxy-5-methylpyrimidin-2(1H)-one 2,4(1H,3H)-Pyrimidinedione, 5-methyl- 5-Methylpyrimidine-2,4-diol ThyMine 5GR 5-Methylpyrimidin-2,4(1H,3H)-dion 2,4-dihydroxy-5-methylpyrimidine D-THYMIDINE THYMIN EINECS 200-616-1 5-Methylpyrimidine-2,4(1H,3H)-dione MFCD00006026 Zidovudine Impurity 3

Description	Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.
Related Catalog	Natural Products >> Saccharides and Glycosides Research Areas >> Cancer Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
References	[1]. Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6.

Density	1.4±0.1 g/cm3
Boiling Point	403.8±37.0 °C at 760 mmHg
Melting Point	316 °C
Molecular Formula	C₅H₆N₂O₂
Molecular Weight	126.113
Flash Point	198.0±26.5 °C
Exact Mass	126.042931
PSA	65.72000
LogP	-2.09
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.614
Storage condition	Store at RT.
Stability	Stable. Incompatible with strong oxidizing agents.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZAPOAK Zeitschrift fuer Allgemeine Mikrobiologie. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086 Ger. Dem. Rep.) V.1- 1960- Volume(issue)/page/year: 12,583,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7246 No. of Facilities: 437 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 4219 (estimated) No. of Female Employees: 2161 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	XP2100000
HS Code	2933599090

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%