Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,1-Bis(p-chlorophenyl)methyl-carbinol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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80-06-8

80-06-8 structure

Name: 1,1-Bis(p-chlorophenyl)methyl-carbinol
Chemical Name: chlorfenethol
CAS Number: 80-06-8
Molecular Formula: C₁₄H₁₂Cl₂O
Molecular Weight: 267.15000
Catalog: Inorganic chemical industry Inorganic salt Metal nitrates and nitrites
Create Date: 2018-04-22 08:00:00
Modify Date: 2025-08-23 22:57:39
Chlorfenethol is a dehydrochlorinase inhibitor. Chlorfenethol can be used as a synergist for insecticide DDT to increase its effect on resistant strains[1].

Name	chlorfenethol
Synonyms	4-chloro-α-(4-chlorophenyl)-α-methylbenzenemethanol 1,1-bis(4-chlorophenyl)ethan-1-ol MFCD00000628 4,4'-Dichloro-alpha-methylbenzhydrol EINECS 201-246-3 4,4’-dichloro-α-methylbenzhydryl alcohol 1,1-bis(4-chlorophenyl)ethanol

Description	Chlorfenethol is a dehydrochlorinase inhibitor. Chlorfenethol can be used as a synergist for insecticide DDT to increase its effect on resistant strains[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	dehydrochlorinase[1]
References	[1]. Maestre-Serrano R, et al. Susceptibility to insecticides and resistance mechanisms in Aedes aegypti from the Colombian Caribbean Region. Pestic Biochem Physiol. 2014 Nov;116:63-73. [2]. W. R. Halliday, et al. Inheritance of Resistance to Permethrin and DDT in the Southern House Mosquito (Diptera: Culicidae), Journal of Economic Entomology, Volume 78, Issue 4, 1 August 1985, Pages 762–767,

Melting Point	69-71°C
Molecular Formula	C₁₄H₁₂Cl₂O
Molecular Weight	267.15000
Exact Mass	266.02700
PSA	20.23000
LogP	4.24920

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DC7875000

CHEMICAL NAME :: Benzhydrol, 4,4'-dichloro-alpha-methyl-

CAS REGISTRY NUMBER :: 80-06-8

BEILSTEIN REFERENCE NO. :: 2505345

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C14-H12-Cl2-O

MOLECULAR WEIGHT :: 267.16

WISWESSER LINE NOTATION :: GR DXQ1&R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARSIM* Agricultural Research Service, USDA Information Memorandum. (Beltsville, MD 20705) Volume(issue)/page/year: 20,8,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,15,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 725 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,148,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay)

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 72,304,1949

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H411
Precautionary Statements	P273
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;N: Dangerous for the environment;
Risk Phrases	R22
Safety Phrases	S22-S36/37/39-S61-S36
RIDADR	2811
RTECS	DC7875000

75-16-1

90-98-2

80-06-8

Literature: Kao, Hsien-Ming; Grey, Clare P.; Pitchumani, Kasi; Lakshminarasimhan; Ramamurthy Journal of Physical Chemistry A, 1998 , vol. 102, # 28 p. 5627 - 5638

141-78-6

80-06-8

Literature: Uddin, Md. Khabir; Fujio, Mizue; Kim, Hyun-Joong; Rappoport, Zvi; Tsuno, Yuho Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 6 p. 1371 - 1379

141-78-6

873-77-8

80-06-8

Literature: Grummitt Science (Washington, DC, United States), 1950 , vol. 111, p. 361

2642-81-1

80-06-8

Literature: Kao, Hsien-Ming; Grey, Clare P.; Pitchumani, Kasi; Lakshminarasimhan; Ramamurthy Journal of Physical Chemistry A, 1998 , vol. 102, # 28 p. 5627 - 5638

917-64-6

90-98-2

80-06-8

Literature: Bergmann; Bondi Chemische Berichte, 1931 , vol. 64, p. 1455,1480 Chemische Berichte, 1933 , vol. 66, p. 286,291 Full Text Show Details Forrest; Stephenson; Waters Journal of the Chemical Society, 1946 , p. 333,339

72-55-9

80-06-8

Literature: Forrest; Stephenson; Waters Journal of the Chemical Society, 1946 , p. 333,339

108-24-7

873-77-8

80-06-8

Literature: Monsanto Chem. Co. Patent: US2704300 , 1953 ;

106-39-8

141-78-6

~86%

80-06-8

Literature: Gao, Fei; Deng, Xiang-Jun; Tang, Yu; Tang, Jin-Peng; Yang, Jun; Zhang, Yuan-Ming Tetrahedron Letters, 2014 , vol. 55, # 4 p. 880 - 883

Precursor 9
106-39-8 141-78-6 75-16-1 90-98-2
873-77-8 2642-81-1 917-64-6 72-55-9
108-24-7
DownStream 3
2642-81-1 90-98-2 3547-04-4

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