26172-54-3

26172-54-3 structure

Name: Methylisothiazolinone hydrochloride
Chemical Name: 2-Methyl-3-isothiazolone Hydrochloride
CAS Number: 26172-54-3
Molecular Formula: C₄H₆ClNOS
Molecular Weight: 151.61500
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-12-28 16:29:41
Modify Date: 2025-08-20 22:46:15
Methylisothiazolinone hydrochloride is the constituent of the biocide Kathon CG. Methylisothiazolinone hydrochloride is an isothiazolone derivative widely used as a preservative. Methylisothiazolinone hydrochloride is also a moderate sensitizer and reacts with GSH[1][2].

Name	2-Methyl-3-isothiazolone Hydrochloride
Synonyms	2-Methyl-3-isothiazoloneHydrochloride MIT,Methylisothiazolinone hydrochloride 2-methyl-1,2-thiazol-3-one,hydrochloride EINECS 247-499-3 MFCD06804636

Description	Methylisothiazolinone hydrochloride is the constituent of the biocide Kathon CG. Methylisothiazolinone hydrochloride is an isothiazolone derivative widely used as a preservative. Methylisothiazolinone hydrochloride is also a moderate sensitizer and reacts with GSH[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Rubén Alvarez-Sánchez, et al. Covalent Binding of the 13C-labeled Skin Sensitizers 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI) to a Model Peptide and Glutathione. Bioorg Med Chem Lett. 2004 Jan 19;14(2):365-8. [2]. Aynur O Aptula, et al. From Experiment to Theory: Molecular Orbital Parameters to Interpret the Skin Sensitization Potential of 5-chloro-2-methylisothiazol-3-one and 2-methylisothiazol-3-one. Chem Res Toxicol. 2005 Feb;18(2):324-9.

Symbol	GHS05, GHS08
Signal Word	Danger
Hazard Statements	H314-H317-H334
Precautionary Statements	P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C
Risk Phrases	34-42/43
Safety Phrases	26-36/37/39-45
RIDADR	UN 1759 8/PG 2
WGK Germany	3
HS Code	2934999090

7791-25-5

1002-19-3

26172-54-3

Literature: Sunkyong Industries Co., Ltd. Patent: US5453507 A1, 1995 ;

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%