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344900-92-1

344900-92-1 structure
344900-92-1 structure
  • Name: FTI-2153
  • Chemical Name: fti-2153
  • CAS Number: 344900-92-1
  • Molecular Formula: C25H30N4O3S
  • Molecular Weight: 466.59600
  • Catalog: Research Areas Cancer
  • Create Date: 2016-02-17 17:15:25
  • Modify Date: 2024-01-19 23:45:11
  • FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity[1].
Name fti-2153
Description FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity[1].
Related Catalog
References

[1]. Sun J, et al. Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine. Cancer Res. 1999 Oct 1;59(19):4919-26.
Molecular Formula C25H30N4O3S
Molecular Weight 466.59600
Exact Mass 466.20400
PSA 121.41000
LogP 4.48120
Hazard Codes Xi

Chemsrc provides CAS#:344900-92-1 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 344900-92-1 | Chemsrc address: https://www.chemsrc.com/en/baike/508319.html

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