15180-02-6
15180-02-6 structure
- Name: amfonelic acid
- Chemical Name: 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
- CAS Number: 15180-02-6
- Molecular Formula: C18H16N2O3
- Molecular Weight: 308.33
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-03-27 08:00:00
- Modify Date: 2024-01-02 16:15:36
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Amfonelic acid (WIN-25978) is a highly selective dopamine reuptake inhibitor. Amfonelic acid interferes with the in vitro neuronal uptake of norepinephrine in the iris of rats, but does not alter the concentrations of norepinephrine or dopamine in the whole mouse brain. Amfonelic acid can be used as a pharmacological tool to study the brain reward system, dopamine pathway and dopamine transporter[1].
| Name | 7-benzyl-1-ethyl-4-oxo-1,8-naphthyridine-3-carboxylic acid |
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| Synonyms |
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-7-(phenylmethyl)-
amfonelic acid 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid Amfonelinsaeure 7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridin-3-carbonsaeure 7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 1-Ethyl-1,4-dihydro-4-oxo-7-(phenylmethyl)-1,8-naphthyridine-3-carboxylic Acid |
| Description | Amfonelic acid (WIN-25978) is a highly selective dopamine reuptake inhibitor. Amfonelic acid interferes with the in vitro neuronal uptake of norepinephrine in the iris of rats, but does not alter the concentrations of norepinephrine or dopamine in the whole mouse brain. Amfonelic acid can be used as a pharmacological tool to study the brain reward system, dopamine pathway and dopamine transporter[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 499.3±45.0 °C at 760 mmHg |
| Molecular Formula | C18H16N2O3 |
| Molecular Weight | 308.33 |
| Flash Point | 255.8±28.7 °C |
| Exact Mass | 308.116089 |
| PSA | 72.19000 |
| LogP | 2.72 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.630 |
| Hazard Codes | Xi |
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| HS Code | 2933990090 |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |