147025-53-4

147025-53-4 structure

Name: Talsaclidine
Chemical Name: (3R)-3-prop-2-ynoxy-1-azabicyclo[2.2.2]octane
CAS Number: 147025-53-4
Molecular Formula: C₁₀H₁₅NO
Molecular Weight: 165.23200
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2016-12-04 19:46:36
Modify Date: 2024-01-02 17:02:27
Talsaclidine is a muscarinic agonist with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes[1][2][3][4].

Name	(3R)-3-prop-2-ynoxy-1-azabicyclo[2.2.2]octane
Synonyms	WAL 2014 Talsaclidine

Description	Talsaclidine is a muscarinic agonist with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes[1][2][3][4].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
References	[1]. Ensinger HA, et al. WAL 2014--a muscarinic agonist with preferential neuron-stimulating properties. Life Sci. 1993;52(5-6):473-80. [2]. Wienrich M, et al. Pharmacodynamic profile of the M1 agonist talsaclidine in animals and man. Life Sci. 2001 Apr 27;68(22-23):2593-600. [3]. Walland A, et al. In vivo consequences of M1-receptor activation by talsaclidine. Life Sci. 1997;60(13-14):977-84. [4]. Walland A, et al. Compensation of muscarinic bronchial effects of talsaclidine by concomitant sympathetic activation in guinea pigs. Eur J Pharmacol. 1997 Jul 9;330(2-3):213-9.

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H318
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R41
Safety Phrases	S26
RIDADR	NONH for all modes of transport