Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Lymecycline
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Purity: 98.0%
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DC Chemicals Limited
China
Product Name: Lymecycline
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: lymecycline
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Purity: 98.0%
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992-21-2

992-21-2 structure

992-21-2 structure

Name: Lymecycline
Chemical Name: lymecycline
CAS Number: 992-21-2
Molecular Formula: C₂₉H₃₈N₄O₁₀
Molecular Weight: 602.63
Catalog: API Antibiotics Tetracycline
Create Date: 2018-08-08 19:28:55
Modify Date: 2025-08-25 15:46:55
Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property.

Name	lymecycline
Synonyms	limecycline [(1r,7ar)-1-hydroxy-2,3,5,7a-tetrahydro-1h-pyrrolizin-7-yl]methyl(2r,3s)-2,3-dihydroxy-2-isopropylbutanoate 2,3-Dihydroxy-2-(1-methylethyl)-butanoic acid (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl) methyl ester lycopsamine (+)-Indicine

Description	Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property.
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
Target	Bacterial[1]
In Vitro	Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity interfering with prokaryotic protein synthesis at the ribosome level. Lymecycline also has anti-inflammatory property[1].
References	[1]. Rempe S, et al. Tetracyclines and pulmonary inflammation. Endocr Metab Immune Disord Drug Targets. 2007 Dec;7(4):232-6.

Density	1.53
Boiling Point	840.5ºC at 760 mmHg
Melting Point	192.5°C
Molecular Formula	C₂₉H₃₈N₄O₁₀
Molecular Weight	602.63
Flash Point	462.1ºC
Exact Mass	602.25900
PSA	242.98000
LogP	1.02790
Index of Refraction	1.693
Water Solubility	Very soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OL5615000

CHEMICAL NAME :: Lysine, N(sup 6)-((4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro -3,6,10,12,12a- pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxa mido)methyl)-, (+)-

CAS REGISTRY NUMBER :: 992-21-2

LAST UPDATED :: 199201

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C29-H38-N4-O10

MOLECULAR WEIGHT :: 602.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 181 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,333,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 253 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 2,106,1964

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