| Name | Luteinizing hormone releasing hormone salmon |
|---|---|
| Synonyms |
pyr-his-trp-ser-tyr-gly-trp-leu-pro-gly-nh2
Pyr-HWSYGWLPG-NH2 Luteinizing Hormone Releasing Hormone (LH-RH), salmon |
| Description | Luteinizing Hormone Releasing Hormone (LH-RH), salmon is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions. |
|---|---|
| Related Catalog | |
| In Vitro | Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells[1]. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells[2]. |
| References |
| Molecular Formula | C60H73N15O13 |
|---|---|
| Molecular Weight | 1212.31000 |
| Exact Mass | 1211.55000 |
| PSA | 426.02000 |
| LogP | 2.37720 |
| Storage condition | -20°C |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360 |
| Precautionary Statements | P201-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R60 |
| Safety Phrases | 53-22-36/37/39-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3.0 |