GL Biochem (Shanghai) Ltd.
China
Product Name: Pyr-HWSYGWLPG-NH2
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: LHRH (salmon) acetate salt
Price: ￥1078.0/5mg ￥378.0/1mg
Purity: 97.0%
Stocking Period: Inquiry
Contact: Liu jia

Zhejiang Hangyu API Co., Ltd
China
Product Name: Luteinizing Hormone Releasing Hormone (LH-RH), salmon
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

86073-88-3

86073-88-3 structure

86073-88-3 structure

Name: LHRH (salmon) acetate salt
Chemical Name: Luteinizing hormone releasing hormone salmon
CAS Number: 86073-88-3
Molecular Formula: C₆₀H₇₃N₁₅O₁₃
Molecular Weight: 1212.31000
Catalog: Peptides
Create Date: 2018-12-31 14:37:38
Modify Date: 2024-01-02 16:33:58
Luteinizing Hormone Releasing Hormone (LH-RH), salmon is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

Name	Luteinizing hormone releasing hormone salmon
Synonyms	pyr-his-trp-ser-tyr-gly-trp-leu-pro-gly-nh2 Pyr-HWSYGWLPG-NH2 Luteinizing Hormone Releasing Hormone (LH-RH), salmon

Description	Luteinizing Hormone Releasing Hormone (LH-RH), salmon is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Peptides
In Vitro	Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells[1]. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells[2].
References	[1]. Moretti RM, et al. Inhibitory activity of luteinizing hormone-releasing hormone on tumor growth and progression. Endocr Relat Cancer. 2003 Jun;10(2):161-7. [2]. Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53.

Molecular Formula	C₆₀H₇₃N₁₅O₁₃
Molecular Weight	1212.31000
Exact Mass	1211.55000
PSA	426.02000
LogP	2.37720
Storage condition	-20°C

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H360
Precautionary Statements	P201-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;
Risk Phrases	R60
Safety Phrases	53-22-36/37/39-45
RIDADR	NONH for all modes of transport
WGK Germany	3.0