13589-06-5

13589-06-5 structure

Name: BNC210
Chemical Name: h-ile-trp-oh
CAS Number: 13589-06-5
Molecular Formula: C₁₇H₂₃N₃O₃
Molecular Weight: 317.38300
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2016-09-30 16:43:04
Modify Date: 2024-01-14 10:06:15
BNC210 (H-Ile-Trp-OH; IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression[1].

Name	h-ile-trp-oh
Synonyms	REF DUPL: H-Ile-Trp-OH L-ISOLEUCYL-L-TRYPTOPHAN BNC210

Description	BNC210 (H-Ile-Trp-OH; IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. Toby Wise, et al. Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalised Anxiety Disorder (GAD) by BNC210, a negative allosteric modulator of α7 nAChR.