131987-54-7

131987-54-7 structure

Name: Tazomeline
Chemical Name: 3-hexylsulfanyl-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
CAS Number: 131987-54-7
Molecular Formula: C₁₄H₂₃N₃S₂
Molecular Weight: 297.48300
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2017-02-16 21:34:09
Modify Date: 2025-08-25 13:05:17
Tazomeline is a selective M1 muscarinic receptor agonist. Tazomeline inhibits twitch height in rabbit vas deferens(IC50= 0.001 nM). Tazomeline can be used for research of neuropsychiatric disorders[1].

Name	3-hexylsulfanyl-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
Synonyms	Tazomeline [INN] (3-Hexylthio)-tztp UNII-QDP6S14W5W Tazomeline 3-(3-Hexylthio-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine 3-(4-hexylthio-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine

Description	Tazomeline is a selective M1 muscarinic receptor agonist. Tazomeline inhibits twitch height in rabbit vas deferens(IC50= 0.001 nM). Tazomeline can be used for research of neuropsychiatric disorders[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
References	[1]. Sauerberg P, et al. Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines . J Med Chem. 1992 Jun 12;35(12):2274-83.

Precursor 1
131988-61-9
DownStream 0