Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Cytochalasin C
Price: ￥1078.0/1mg ￥3578.0/5mg
Purity: 97.0%
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22144-76-9

22144-76-9 structure

22144-76-9 structure

Name: Cytochalasin C
Chemical Name: cytochalasin c
CAS Number: 22144-76-9
Molecular Formula: C₃₀H₃₇NO₆
Molecular Weight: 507.618
Catalog: Biochemical Plant extracts
Create Date: 2018-06-22 11:59:07
Modify Date: 2024-01-03 22:47:35
Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3].

Name	cytochalasin c
Synonyms	1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-, (7Z,13E)- Acétate de (7Z,13E)-3-benzyl-6,12-dihydroxy-4,5,10,12-tétraméthyl-1,11-dioxo-2,3,3a,6,6a,9,10,11,12,15-décahydro-1H-cycloundéca[d]isoindol-15-yle EINECS 244-803-6 (7Z,13E)-3-Benzyl-6,12-dihydroxy-4,5,10,12-tetramethyl-1,11-dioxo-2,3,3a,6,6a,9,10,11,12,15-decahydro-1H-cycloundeca[d]isoindol-15-ylacetat (7Z,13E)-3-Benzyl-6,12-dihydroxy-4,5,10,12-tetramethyl-1,11-dioxo-2,3,3a,6,6a,9,10,11,12,15-decahydro-1H-cycloundeca[d]isoindol-15-yl acetate Cytochalasin C from Metarrhizium anisopliae MFCD00066080

Description	Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Foissner I, et al. Wide-ranging effects of eight cytochalasins and latrunculin A and B on intracellular motility and actin filament reorganization in characean internodal cells. Plant Cell Physiol. 2007 Apr;48(4):585-97. [2]. Yahara I, et al. Correlation between effects of 24 different cytochalasins on cellular structures and cellular eventsand those on actin in vitro. J Cell Biol. 1982 Jan;92(1):69-78. [3]. Trendowski M, et al. Tolerated doses in zebrafish of cytochalasins and jasplakinolide for comparison with tolerateddoses in mice in the evaluation of pre-clinical activity of microfilament-directed agents in tumormodel systems in vivo. In Vivo. 2014 Nov-Dec;28(6):1021-31.

Density	1.2±0.1 g/cm3
Boiling Point	714.3±60.0 °C at 760 mmHg
Melting Point	260-264ºC
Molecular Formula	C₃₀H₃₇NO₆
Molecular Weight	507.618
Flash Point	385.8±32.9 °C
Exact Mass	507.262085
PSA	112.93000
LogP	2.81
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.602
Storage condition	−20°C
Water Solubility	methylene chloride: 5 mg/mL, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA5300500

CHEMICAL NAME :: (11)Cytochalasa-5,13,19-triene-1,17-dione, 21-(acetoxy)-7,18-dihydroxy-16,18-dimethyl- 10-phenyl-, (7S,13E,16S,18R,19E,21R)-

CAS REGISTRY NUMBER :: 22144-76-9

LAST UPDATED :: 199203

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 21,2268,1973

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H300 + H310 + H330-H361
Precautionary Statements	P260-P264-P280-P284-P301 + P310-P302 + P350
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+: Very toxic;T: Toxic;
Risk Phrases	26/27/28-63
Safety Phrases	28-36/37-45
RIDADR	UN 1544 6.1/PG 2
WGK Germany	3
RTECS	HA5300500
Packaging Group	I
Hazard Class	6.1(a)