Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Juglone
Price: ￥398.0/20mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 5-Hydroxy-1,4-naphthalenedione
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: 5-Hydroxy-1,4-naphthalenedione
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

481-39-0

481-39-0 structure

481-39-0 structure

Name: Juglone
Chemical Name: juglone
CAS Number: 481-39-0
Molecular Formula: C₁₀H₆O₃
Molecular Weight: 174.153
Catalog: Chemical reagent Organic reagent Aromatic ketone
Create Date: 2018-03-24 08:00:00
Modify Date: 2024-01-02 17:50:16
Juglone is a yellow pigment found in black walnut (Juglans regia). Juglone also shows antimicrobial activity[1].

Name	juglone
Synonyms	Nucin Juglone EINECS 207-567-5 5-Hydroxy-1,4-naphthalenedione C.I. Natural Brown 7 5-hydroxynaphthalene-1,4-dione Regianin CI 75500 5-hydroxy-1,4-dihydronaphthalene-1,4-dione 5-Hydroxy-1,4-naphthochinone 1,4-Naphthalenedione, 5-hydroxy- 5-HNQ 5-Hydroxy-p-naphthoquinone MFCD00001684 5-Hydroxy-1,4-naphthoquinone

Description	Juglone is a yellow pigment found in black walnut (Juglans regia). Juglone also shows antimicrobial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. J. Johnson Inbaraj, et al. Cytotoxic Action of Juglone and Plumbagin: A Mechanistic Study Using HaCaT Keratinocytes.Chem. Res. Toxicol. 2004, 17, 1, 55-62

Density	1.4±0.1 g/cm3
Boiling Point	385.8±42.0 °C at 760 mmHg
Melting Point	161-163 °C(lit.)
Molecular Formula	C₁₀H₆O₃
Molecular Weight	174.153
Flash Point	201.3±24.4 °C
Exact Mass	174.031693
PSA	54.37000
LogP	1.86
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.662
Storage condition	Refrigerator (+4°C)
Water Solubility	SOLUBLE IN HOT WATER

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ5775000

CHEMICAL NAME :: 1,4-Naphthalenedione, 5-hydroxy-

CAS REGISTRY NUMBER :: 481-39-0

BEILSTEIN REFERENCE NO. :: 1909764

LAST UPDATED :: 199706

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H6-O3

MOLECULAR WEIGHT :: 174.16

WISWESSER LINE NOTATION :: L66 BV EVJ GQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 394 mg/kg/53W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 10 mg/kg

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 126,583,1967

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H315-H319-H335-H400
Precautionary Statements	P261-P273-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25;R36/37/38
Safety Phrases	S22-S26-S36/37/39-S45-S37/39-S28A
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	QJ5775000
Packaging Group	III
Hazard Class	6.1
HS Code	2914690090

Precursor 7
83-56-7 496-64-0 106-51-4 569-42-6
5196-28-1 115031-12-4 481-40-3
DownStream 10
481-72-1 477-85-0 481-74-3 67116-22-7
18855-92-0 18713-45-6 481-42-5 14777-17-4
80596-51-6 129-43-1

HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%