94-67-7

94-67-7 structure

Name: salicylaldehyde, oxime
Chemical Name: Salicylaldoxime
CAS Number: 94-67-7
Molecular Formula: C₇H₇NO₂
Molecular Weight: 137.136
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Thiophene
Create Date: 2018-03-01 08:00:00
Modify Date: 2025-08-22 15:19:56
Salicylaldoxime is an organic compound, that has been used as a reagent for the gravimetric determination and separation of Cooper, Nickel, Palladium, Lead, Bismuth and Zine. The copper complex of Salicylaldoxime has anticancer activity[1][2].

Name	Salicylaldoxime
Synonyms	2-hydroxybenzaldehyde oxime salicylaldehyde, oxime Saldox Benzaldehyde, 2-hydroxy-, oxime SALICYLALDEHYDE OXIME Salicylaldehydoxime 2-hydroxybenzaldoxime SalicyladoximeGr o-Hydroxybenzaldoxime MFCD00002120 o-hydroxybenzaldehyde oxime EINECS 202-353-8 2-[(Hydroxyimino)methyl]phenol Salicaldehyde oxime 2-[(E)-(Hydroxyimino)methyl]phenol

Description	Salicylaldoxime is an organic compound, that has been used as a reagent for the gravimetric determination and separation of Cooper, Nickel, Palladium, Lead, Bismuth and Zine. The copper complex of Salicylaldoxime has anticancer activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Salicylaldoxime (300 μM) completely inhibits the relaxation activity of topoisomerase II when it forms a complex with copper; also inhibits L1210 leukaemia cell proliferation[1].
References	[1]. W Ligett and L Biefeld. Separation and Determination of Lead with Salicylaldoxime. Ind. Eng. Chem. Anal. Ed. 1941, 13, 11, 813-815. [2]. D. Jayaraju and Anand K. Kondapi. Anti-cancer copper salicylaldoxime complex inhibits topoisomerase II catalytic activity. Current Science. Vol. 81, No. 7 (10 October 2001), pp. 787-792

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,36,1953

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	VN5775000