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83-73-8

83-73-8 structure
83-73-8 structure
Name 5,7-Diiodo-8-hydroxyquinoline
Synonyms Disoquin
Dyodin
Rafamebin
ZOAQUIN
Diiodo-oxyquinoline
8-Hydroxy-5,7-diiodoquinoline
EINECS 201-497-9
Searlequin
5,7-diiodoquinolin-8-ol
Yodoxin
5,7-Diiodooxine
Diiodohydroxyquinolin
MFCD00006789
8-Quinolinol, 5,7-diiodo-
Dinoleine
Embequin
IODOQUINOL
Diiodohydroxyquinoline
Stanquinate
Enterosept
Iodoquinol (USP)
Diodoquin
Ioquin
Direxiode
5,7-Diiodo-8-quinolinol
Diodoxylin
Diiodoquinol
Description Diiodohydroxyquinoline is a topical therapeutic agent, with satisfactory antibacterial properties.
Related Catalog
Density 2.5±0.1 g/cm3
Boiling Point 401.8±45.0 °C at 760 mmHg
Melting Point >200 °C (dec.)(lit.)
Molecular Formula C9H5I2NO
Molecular Weight 396.951
Flash Point 196.8±28.7 °C
Exact Mass 396.846039
PSA 33.12000
LogP 4.11
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.828

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC5775000
CHEMICAL NAME :
8-Quinolinol, 5,7-diiodo-
CAS REGISTRY NUMBER :
83-73-8
BEILSTEIN REFERENCE NO. :
0153639
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C9-H5-I2-N-O
MOLECULAR WEIGHT :
396.95
WISWESSER LINE NOTATION :
T66 BNJ GI II JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
819 mg/kg/13D-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Blood - oxidant related (GPD deficient) anemia
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
120 gm/kg/2Y-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - visual field changes
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>40 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Liver - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Liver - other changes

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 222,219,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80403 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated)
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H318
Precautionary Statements P280-P305 + P351 + P338
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S26-S36/37/39
RIDADR 3249
WGK Germany 3
RTECS VC5775000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2933499090
148-24-3 structure

148-24-3

~98%

83-73-8 structure

83-73-8

Literature: Lista, Liliana; Pezzella, Alessandro; Napolitano, Alessandra; d'Ischia, Marco Tetrahedron, 2008 , vol. 64, # 1 p. 234 - 239
148-24-3 structure

148-24-3

~%

13207-63-1 structure

13207-63-1

83-73-8 structure

83-73-8

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2> 145, p. 257,261
220819-23-8 structure

220819-23-8

~%

83-73-8 structure

83-73-8

110-15-6 structure

110-15-6

443-48-1 structure

443-48-1

Detail
Literature: Scientia Pharmaceutica, , vol. 66, # 4 p. 309 - 324
220819-28-3 structure

220819-28-3

~%

83-73-8 structure

83-73-8

88-99-3 structure

88-99-3

443-48-1 structure

443-48-1

Detail
Literature: Scientia Pharmaceutica, , vol. 66, # 4 p. 309 - 324
7647-01-0 structure

7647-01-0

148-24-3 structure

148-24-3

7732-18-5 structure

7732-18-5

7790-99-0 structure

7790-99-0

~%

Detail
Literature: Journal of Organic Chemistry, , vol. 22, p. 1111
123-91-1 structure

123-91-1

130-26-7 structure

130-26-7

7732-18-5 structure

7732-18-5

~%

773-76-2 structure

773-76-2

Detail
Literature: Chemische Berichte, , vol. 85, p. 104,106
HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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