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773-76-2

773-76-2 structure
773-76-2 structure
  • Name: Chloroxine
  • Chemical Name: chloroxine
  • CAS Number: 773-76-2
  • Molecular Formula: C9H5Cl2NO
  • Molecular Weight: 214.048
  • Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
  • Create Date: 2018-03-25 08:00:00
  • Modify Date: 2025-08-20 19:36:42
  • Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.Target: AntibacterialChloroxine is an antibacterial drug. Oral formulations are used in infectious diarrhea, disorders of the intestinal microflora (e.g. after antibiotic treatment), giardiasis, inflammatory bowel disease. It is also useful for dandruff and seborrheic dermatitis, as used in shampoos and dermal creams like. Chloroxine has bacteriostatic, fungistatic and antiprotozoal properties. It is effective against Streptococci, Staphylococci, Candida, Candida albicans, Shigella and Trichomonads.
Name chloroxine
Synonyms 5,7-Dichloro-8-quinolinol
5,7-Dichloro-8-hydroxyquinoline
EINECS 212-258-3
Chloroxine
5,7-dichloroquinolin-8-ol
8-Quinolinol, 5,7-dichloro-
MFCD00006786
Description Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.Target: AntibacterialChloroxine is an antibacterial drug. Oral formulations are used in infectious diarrhea, disorders of the intestinal microflora (e.g. after antibiotic treatment), giardiasis, inflammatory bowel disease. It is also useful for dandruff and seborrheic dermatitis, as used in shampoos and dermal creams like. Chloroxine has bacteriostatic, fungistatic and antiprotozoal properties. It is effective against Streptococci, Staphylococci, Candida, Candida albicans, Shigella and Trichomonads.
Related Catalog
References

[1]. http://www.drugs.com/cons/chloroxine-topical.html
Density 1.5±0.1 g/cm3
Boiling Point 354.7±37.0 °C at 760 mmHg
Melting Point 178-180 °C(lit.)
Molecular Formula C9H5Cl2NO
Molecular Weight 214.048
Flash Point 168.3±26.5 °C
Exact Mass 212.974823
PSA 33.12000
LogP 3.75
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.702
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC5350000
CHEMICAL NAME :
8-Quinolinol, 5,7-dichloro-
CAS REGISTRY NUMBER :
773-76-2
BEILSTEIN REFERENCE NO. :
0153606
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H5-Cl2-N-O
MOLECULAR WEIGHT :
214.05

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
100 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 307,141,1994
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39-S25-S22
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS VC5350000
HS Code 2933499090
1419402-06-4 structure

1419402-06-4

~%

492-61-5 structure

492-61-5

773-76-2 structure

773-76-2

Literature: Dalton Transactions, , vol. 42, # 6 p. 2023 - 2034
148-24-3 structure

148-24-3

~%

773-76-2 structure

773-76-2

Literature: Chemische Berichte, , vol. 21, p. 2979,2983
687638-05-7 structure

687638-05-7

~%

773-76-2 structure

773-76-2

Literature: Chemische Berichte, , vol. 21, p. 2979,2983
148-24-3 structure

148-24-3

~%

773-76-2 structure

773-76-2

130-16-5 structure

130-16-5

Literature: Journal of the Indian Chemical Society, , vol. 22, p. 171
609-89-2 structure

609-89-2

56-81-5 structure

56-81-5

~%

773-76-2 structure

773-76-2

Literature: Journal of the Indian Chemical Society, , vol. 21, p. 354,356
123-91-1 structure

123-91-1

130-26-7 structure

130-26-7

7732-18-5 structure

7732-18-5

~%

773-76-2 structure

773-76-2

Detail
Literature: Chemische Berichte, , vol. 85, p. 104,106
HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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