DC Chemicals Limited
China
Product Name: KD 5170
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

940943-37-3

940943-37-3 structure

940943-37-3 structure

Name: KD5170
Chemical Name: S-(2-{6-[({4-[3-(Dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p yridinyl}-2-oxoethyl) ethanethioate
CAS Number: 940943-37-3
Molecular Formula: C₂₀H₂₅N₃O₅S₂
Molecular Weight: 451.56000
Create Date: 2017-09-20 15:25:00
Modify Date: 2024-01-14 19:30:34
KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].

Name	S-(2-{6-[({4-[3-(Dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p yridinyl}-2-oxoethyl) ethanethioate
Synonyms	2-PETA Ethanethioic acid,S-[2-(2-pyridinyl)ethyl] ester thioacetic acid S-(2-{6-[4-(3-dimethylaminopropoxy)benzenesulfonylamino]pyridin-3-yl}-2-oxoethyl) ester S-2-(2-pyridyl)ethyl thioacetate thioacetic acid S-(2-[2]pyridyl-ethyl ester) 2-(2-Acetylthio-ethyl)-pyridin 2-pyridylethyl thioacetate Thioessigsaeure-S-(2-[2]pyridyl-aethylester)

Description	KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
References	[1]. Hassig CA, et al. KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 May;7(5):1054-65.

Molecular Formula	C₂₀H₂₅N₃O₅S₂
Molecular Weight	451.56000
Exact Mass	451.12400
PSA	139.35000
LogP	3.82910

940943-40-8 structure

940943-40-8

10387-40-3 structure

10387-40-3

~27%

940943-37-3 structure

940943-37-3

Literature: KALYPSYS, INC. Patent: WO2008/73733 A1, 2008 ; Location in patent: Page/Page column 45; 47-48 ; WO 2008/073733 A1