KD5170

Modify Date: 2025-08-25 13:41:59

Use of KD5170

KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].

Name	S-(2-{6-[({4-[3-(Dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p yridinyl}-2-oxoethyl) ethanethioate
Synonym	More Synonyms

Description	KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
References	[1]. Hassig CA, et al. KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 May;7(5):1054-65.

Molecular Formula	C₂₀H₂₅N₃O₅S₂
Molecular Weight	451.56000
Exact Mass	451.12400
PSA	139.35000
LogP	3.82910
InChIKey	KXWBUKMWZKTHCV-UHFFFAOYSA-N
SMILES	CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(OCCCN(C)C)cc2)nc1

N-(5-Acetyl-pyr...

CAS#:940943-40-8

Potassium thioa...

CAS#:10387-40-3

~27%

KD5170

CAS#:940943-37-3

Literature: KALYPSYS, INC. Patent: WO2008/73733 A1, 2008 ; Location in patent: Page/Page column 45; 47-48 ; WO 2008/073733 A1

2-PETA

Ethanethioic acid,S-[2-(2-pyridinyl)ethyl] ester

thioacetic acid S-(2-{6-[4-(3-dimethylaminopropoxy)benzenesulfonylamino]pyridin-3-yl}-2-oxoethyl) ester

S-2-(2-pyridyl)ethyl thioacetate

thioacetic acid S-(2-[2]pyridyl-ethyl ester)

2-(2-Acetylthio-ethyl)-pyridin

2-pyridylethyl thioacetate

Thioessigsaeure-S-(2-[2]pyridyl-aethylester)

Get all suppliers and price by the below link: