Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Helvolic acid
Price: Check
Purity: 96.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

29400-42-8

29400-42-8 structure

29400-42-8 structure

Name: Helvolic acid
Chemical Name: helvolic acid
CAS Number: 29400-42-8
Molecular Formula: C₃₃H₄₄O₈
Molecular Weight: 568.69800
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-03-09 08:00:00
Modify Date: 2025-08-25 10:17:58
Helvolic acid (Fumigacin) is an antibiotic isolated from Xylaria sp, active against the Gram-positive bacteria[1].

Name	helvolic acid
Synonyms	hervolic acid helvol acid Helvolsaeure Helvolic acid Fumigacin (2Z)-2-[(4S,5S,6S,8S,9S,10R,13R,14S,16S)-6,16-diacetyloxy-4,8,10,14-tetramethyl-3,7-dioxo-5,6,9,11,12,13,15,16-octahydro-4H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid

Description	Helvolic acid (Fumigacin) is an antibiotic isolated from Xylaria sp, active against the Gram-positive bacteria[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Ratnaweera PB, et al. Helvolic acid, an antibacterial nortriterpenoid from a fungal endophyte, Xylaria sp. of orchid Anoectochilus setaceus endemic to Sri Lanka. Mycology. 2014 Mar;5(1):23-28. Epub 2014 Mar 25.

Density	1.2g/cm3
Boiling Point	675.9ºC at 760 mmHg
Molecular Formula	C₃₃H₄₄O₈
Molecular Weight	568.69800
Flash Point	209ºC
Exact Mass	568.30400
PSA	124.04000
LogP	5.40010
Vapour Pressure	5.01E-20mmHg at 25°C
Index of Refraction	1.556

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RC1370000

CHEMICAL NAME :: 29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4-alpha, 6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-bet a)-

CAS REGISTRY NUMBER :: 29400-42-8

BEILSTEIN REFERENCE NO. :: 3230584

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C33-H44-O8

MOLECULAR WEIGHT :: 568.77

WISWESSER LINE NOTATION :: L E5 B666 FY LV OV PUTJ A1 FUYVQ3UY1&1 GOV1 I1 J1 KOV1 N1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 3,1837,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 3,1837,1978

RTECS	RC1370000

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.