1224713-90-9

1224713-90-9 structure

Name: 4'-Bromo-resveratrol
Chemical Name: 5-[(E)-2-(4-bromophenyl)ethenyl]benzene-1,3-diol
CAS Number: 1224713-90-9
Molecular Formula: C₁₄H₁₁BrO₂
Molecular Weight: 291.14000
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-06-10 12:30:52
Modify Date: 2024-01-04 18:18:01
4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling[1].

Name	5-[(E)-2-(4-bromophenyl)ethenyl]benzene-1,3-diol
Synonyms	4-Bromo-Resveratrol

Description	4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin
References	[1]. George J, et al. 4'-Bromo-resveratrol, a dual Sirtuin-1 and Sirtuin-3 inhibitor, inhibits melanoma cell growth through mitochondrial metabolic reprogramming. Mol Carcinog. 2019;58(10):1876-1885.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
RIDADR	NONH for all modes of transport