Name | fomepizole |
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Synonyms |
4-Methylpyrazol
4-MP EINECS 231-445-0 Fomepizolefreebase 4-methyl-pyrazol Antizol-Vet 1H-4-methylpyrazole 4-Methyl-1H-pyrazole Antizol 4-METHYLPYRRAZOLE 3-methyl-1H-pyrazole 1H-Pyrazole, 4-methyl- 4-Methylpyrazole T5MNJ D1 4-methyl-1H-pyrazol Fomepizole fomepizol MFCD00005245 |
Description | Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase which plays a key role in the metabolism of ethylene glycol and methanol. |
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Related Catalog | |
References |
[1]. Casavant MJ. Fomepizole in the treatment of poisoning. Pediatrics. 2001 Jan;107(1):170. |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 243.6±0.0 °C at 760 mmHg |
Melting Point | 13°C |
Molecular Formula | C4H6N2 |
Molecular Weight | 82.104 |
Flash Point | 96.1±0.0 °C |
Exact Mass | 82.053101 |
PSA | 28.68000 |
LogP | 0.78 |
Vapour Pressure | 0.1±0.4 mmHg at 25°C |
Index of Refraction | 1.523 |
Storage condition | 2-8°C |
Water Solubility | soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xn:Harmful; |
Risk Phrases | R22;R36/37/38 |
Safety Phrases | S26-S36-S24/25 |
RIDADR | 2810 |
WGK Germany | 3 |
RTECS | UQ7350000 |
Packaging Group | III |
Hazard Class | 6.1(b) |
HS Code | 2933199090 |
~84% 7554-65-6 |
Literature: Reardan, Dayton T.; Combe, Michel D. Patent: US2007/244330 A1, 2007 ; Location in patent: Page/Page column 2; 3 ; |
~% 7554-65-6 |
Literature: Chemische Berichte, , vol. 33, p. 3595 |
~% 7554-65-6 |
Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2> 65, p. 389 |
Precursor 2 | |
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DownStream 6 | |
HS Code | 2933199090 |
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Summary | 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |