1338-43-8

1338-43-8 structure

Name: Span 80
Chemical Name: Span 80
CAS Number: 1338-43-8
Molecular Formula: C₂₄H₄₄O₆
Molecular Weight: 428.603
Catalog: Surfactant Nonionic surfactant Polyol ester type
Create Date: 2018-04-25 08:00:00
Modify Date: 2024-01-01 21:42:35
Sorbitan monooleate is a renewable polyol with unique molecular structures for the development and design of bio-based waterborne polyurethane (WPU) with versatility and excellent mechanical properties. Sorbitan monooleate can be used as an excipient, such as nonionic surfactants, emulsifiers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Name	Span 80
Synonyms	Sorbitane monooleate,sorbitan oleate Sorbitan Monooleate armotanmo EINECS 215-665-4 sorgen40 o250 Oleic acid compound with (2R,3R,4S)-2-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol glycomulo montan80 (R)-1-((2S,3R,4S)-3,4-Dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl oleate ml33f ml55f mo33f (Sorbitan Monooleate) MFCD00080948 ionets80

Description	Sorbitan monooleate is a renewable polyol with unique molecular structures for the development and design of bio-based waterborne polyurethane (WPU) with versatility and excellent mechanical properties. Sorbitan monooleate can be used as an excipient, such as nonionic surfactants, emulsifiers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Deng H, et al. UV resistance, anticorrosion and high toughness bio-based waterborne polyurethane enabled by a Sorbitan monooleate[J]. Chemical Engineering Journal, 2022, 446: 137124. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Density	1.1±0.1 g/cm3
Boiling Point	579.3±50.0 °C at 760 mmHg
Melting Point	0.986ºC
Molecular Formula	C₂₄H₄₄O₆
Molecular Weight	428.603
Flash Point	186.2±23.6 °C
Exact Mass	428.313782
PSA	96.22000
LogP	7.14
Vapour Pressure	0.0±3.6 mmHg at 25°C
Index of Refraction	1.506
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - pigmented or nucleated red blood cells

REFERENCE :: BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 45,630,1971 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),65,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83475 No. of Facilities: 11289 (estimated) No. of Industries: 95 No. of Occupations: 73 No. of Employees: 71826 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83475 No. of Facilities: 14163 (estimated) No. of Industries: 127 No. of Occupations: 106 No. of Employees: 200724 (estimated) No. of Female Employees: 58462 (estimated)

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	T+
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	WG2932400
HS Code	34021300

HS Code	34021300