78636-53-0

78636-53-0 structure

Name: 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine
Chemical Name: 2'-fluoro-5-methylarabino-furanosylcytosine
CAS Number: 78636-53-0
Molecular Formula: C₁₀H₁₄FN₃O₄
Molecular Weight: 259.23
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-03-20 22:37:33
Modify Date: 2024-01-09 11:02:40
2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Name	2'-fluoro-5-methylarabino-furanosylcytosine
Synonyms	2(1H)-Pyrimidinone,4-amino-1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-5-ethyl

Description	2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.