Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Protosappanin B
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Protosappanin B
Price: ￥4480.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Protosappanin B
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

102036-29-3

102036-29-3 structure

102036-29-3 structure

Name: Protosappanin B
Chemical Name: Protosappanin B
CAS Number: 102036-29-3
Molecular Formula: C₁₆H₁₆O₆
Molecular Weight: 304.29
Catalog: Natural product Phenols
Create Date: 2018-02-12 08:00:00
Modify Date: 2025-08-27 12:44:47
Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].

Name	Protosappanin B
Synonyms	(7S)-7-(Hydroxymethyl)-7,8-dihydro-6H-dibenzo[b,d]oxocine-3,7,10,11-tetrol 6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol, 7,8-dihydro-7-(hydroxymethyl)-, (7S)-

Description	Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
Target	Apoptosis[2]
In Vitro	Protosappanin B (12.5, 25, 50, 100, 200 µg/mL, 48 hours) dose-dependently inhibits tumor cells, with IC50s of 21.32 µg/mL, 26.73 µg/mL, and 76.53 µg/mL for SW-480, HCT-116, and BTT cells, respectively[1]. Cell Viability Assay[1] Cell Line: CT-116, SW-480, and BTT Cells Concentration: 12.5, 25, 50, 100, 200 µg/mL Incubation Time: 48 hours Result: Dose-dependently inhibited tumor cells after 48 hours of treatment.
References	[1]. Yang X, et al. Antitumor Effects of Purified Protosappanin B Extracted From Lignum Sappan. Integr Cancer Ther. 2016 Mar;15(1):87-95. [2]. Yang X, et al. Protosappanin B promotes apoptosis and causes G1 cell cycle arrest in human bladder cancer cells. Sci Rep. 2019 Jan 31;9(1):1048.

Density	1.5±0.1 g/cm3
Boiling Point	655.5±55.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₆O₆
Molecular Weight	304.29
Flash Point	350.2±31.5 °C
Exact Mass	304.094696
PSA	110.38000
LogP	1.13
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.700
Storage condition	2~8℃

Hazard Codes	Xi

130233-78-2 structure

130233-78-2

~%

474-07-7 structure

474-07-7

102036-29-3 structure

102036-29-3

Literature: Chemical and Pharmaceutical Bulletin, , vol. 38, # 6 p. 1490 - 1494

111534-98-6 structure

111534-98-6

~%

102036-29-3 structure

102036-29-3

Literature: Chemical & Pharmaceutical Bulletin, , vol. 35, # 7 p. 3002 - 3005

Precursor 1
111534-98-6
DownStream 0

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