486-89-5

486-89-5 structure

Name: Anagyrine
Chemical Name: anagyrine
CAS Number: 486-89-5
Molecular Formula: C₁₅H₂₀N₂O
Molecular Weight: 244.33200
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-09-06 20:44:33
Modify Date: 2025-08-27 17:14:49
Anagyrine is an alkaloid that has been found in L. albus and has nematocidal and anticancer activities[1].It binds to muscarinic and nicotinic acetylcholine receptors (AChRs) with IC50 values of 132 and 2096 µM respectively[2].

Name	anagyrine
Synonyms	Anagyrin Monolupine 3,4,5,6-Tetradehydrospartein-2-one RHOMBININE Alkaloid III Rhombinin Monolupin

Description	Anagyrine is an alkaloid that has been found in L. albus and has nematocidal and anticancer activities[1].It binds to muscarinic and nicotinic acetylcholine receptors (AChRs) with IC50 values of 132 and 2096 µM respectively[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR
References	[1]. Schmeller T, Sauerwein M, Sporer F, Wink M, Müller WE. Binding of quinolizidine alkaloids to nicotinic and muscarinic acetylcholine receptors. J Nat Prod. 1994 Sep;57(9):1316-9. [2]. Matsuda, K., et al. Nematicidal activities of (–)-N-methylcytisine and (–)-anagyrine from Sophora flavescens against pine wood nematodes. Agr. BioI. Chem. 53(8), 2287-2288 (1989).

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 1,887,1976