Name | N-(6-oxo-3,7-dihydropurin-2-yl)acetamide |
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Synonyms |
2-Acetamido-6-hydroxypurine
N2-Acetylguanine N2-acetylguanidine N-2-Acetylguanine MFCD00078201 N-Acetylguanine 2-acetylamino-6-hydroxypurine 2-N-Acetylguanine EINECS 243-443-7 |
Description | N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1]. |
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Related Catalog | |
In Vitro | N2-Acetylguanine completely disrupt a key Watson–Crick pairing interaction between the ligand and RNA[1]. N2-Acetylguanine (20 µM) promotes transcriptional termination in Bacillus subtilis [1]. |
References |
Density | 1.83 g/cm3 |
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Melting Point | 260 °C |
Molecular Formula | C7H7N5O2 |
Molecular Weight | 193.16300 |
Exact Mass | 193.06000 |
PSA | 103.53000 |
Index of Refraction | 1.833 |
Storage condition | Refrigerator |
Water Solubility | practically insoluble |
Hazard Codes | Xi: Irritant; |
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Risk Phrases | R36/37/38 |
Safety Phrases | S24/25 |
HS Code | 2933990090 |
~% 19962-37-9 |
Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727 |
~% 19962-37-9 |
Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727 |
~% 19962-37-9 |
Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727 |
~% 19962-37-9 |
Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 10-12 p. 1707 - 1727 |
Precursor 1 | |
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DownStream 10 | |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |