DC Chemicals Limited
China
Product Name: ZPCK
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Carbamic acid,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

26049-94-5

26049-94-5 structure

26049-94-5 structure

Name: zpck
Chemical Name: benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate
CAS Number: 26049-94-5
Molecular Formula: C₁₈H₁₈ClNO₃
Molecular Weight: 331.793
Catalog: Biochemical Amino acids and their derivatives Cbz-amino acid
Create Date: 2019-01-11 01:18:09
Modify Date: 2024-01-10 07:36:54
ZPCK is an oral active prodrug of gemcitabine that was designed for improved oral bioavailability[1].

Name	benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate
Synonyms	(3S)-3-benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanone Carbamic acid, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester benzyl (S)-(1-benzyl-3-chloro-2-oxopropyl)carbamate N-Carbobenzoxy-L-phenylalanyl-chloromethyl ketone Lopac-C-9511 N-benzyloxycarbonyl-L-phenylalanine chloromethyl ketone MFCD00037114 N-CBZ-L-phenylalanine chloromethyl ketone Benzyl [(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate ZPCK N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone Carbamic acid, [3-chloro-2-oxo-1- (phenylmethyl)propyl]-, phenylmethyl ester, (S)- L-Carbobenzyloxyphenylalanyl chloromethyl ketone Carbamic acid, [3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester, (S)- (S)-(1-benzyl-3-chloro-2-oxopropyl)carbamic acid benzyl ester EINECS 247-432-8 Z-L-Phe chloromethyl ketone Benzyl [(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]carbamate Benzyl [(1S)-1-benzyl-3-chloro-2-oxopropyl]carbamate Z-Phe-CH2Cl [N-(benzyloxycarbonyl)-L-phenylalanyl]methyl chloride N-[(1S)-3-Chloro-2-Oxo-1-(Phenylmethyl)Propyl]-Carbamic Acid Phenylmethyl Ester Z-Phe-CMK

Description	ZPCK is an oral active prodrug of gemcitabine that was designed for improved oral bioavailability[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Autophagy >> Autophagy
References	[1]. Zhao C, et al. Pharmacokinetics and metabolism of SL-01, a prodrug of gemcitabine, in rats. Cancer Chemother Pharmacol. 2013 Jun;71(6):1541-50.

Density	1.2±0.1 g/cm3
Boiling Point	503.1±50.0 °C at 760 mmHg
Melting Point	107-108ºC(lit.)
Molecular Formula	C₁₈H₁₈ClNO₃
Molecular Weight	331.793
Flash Point	258.1±30.1 °C
Exact Mass	331.097534
PSA	55.40000
LogP	4.28
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.573
Storage condition	-15°C

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C
Risk Phrases	R34
Safety Phrases	26-27-36/37/39-45
RIDADR	UN 3261 8
WGK Germany	3
HS Code	2924299090

Precursor 8
34351-19-4 501-53-1 15196-02-8 593-71-5
28709-70-8 1161-13-3 35909-92-3 41518-17-6
DownStream 4
25487-25-6 128018-43-9 128018-44-0 160231-69-6

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%