60-25-3

60-25-3 structure
60-25-3 structure

Name hexamethonium chloride
Synonyms chloor-hexaviet
hiohexchloride
hestriumchloride
methiumchloride
hexonchloride
hexonechloride
a,w-bis(trimethylammonium)hexane dichloride
1,6-Di(trimethylammonium)hexamethylene dichloride
hexamethylene bis-(trimethyl ammonium) chloride
esomidchloride
MFCD00031563
Hexa-N-methyl-N,N'-hexandiyl-di-ammonium,Dichlorid
hexa-N-methyl-N,N'-hexanediyl-di-ammonium,dichloride
1,6-Hexanediaminium, N,N,N,N,N,N-hexamethyl-, chloride (1:2)
α,ω-Bis(trimethylammonium)hexane dichloride
hexametonchloride
N,N,N,N',N',N'-Hexamethylhexane-1,6-diaminium dichloride
bistriumchloride
N,N,N,N',N',N'-Hexamethyl-1,6-hexanediaminium dichloride
EINECS 200-465-1
depressin
hexamethonium dichloride
Description Hexamethonium Chloride Dihydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
Melting Point 292 °C(dec.)
Molecular Formula C12H30Cl2N2
Molecular Weight 273.286
Exact Mass 272.178589

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BQ8650000
CHEMICAL NAME :
Ammonium, hexamethylenebis(trimethyl-, dichloride
CAS REGISTRY NUMBER :
60-25-3
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C12-H30-N2.2Cl
MOLECULAR WEIGHT :
273.34
WISWESSER LINE NOTATION :
1K1&1&6K1&1&1 &Q 2 &G 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,346,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
62 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 155,69,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
26700 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 127,1,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,346,1957
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
RTECS BQ8650000
HS Code 2923900090
Precursor  2

DownStream  0

HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%