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124511-67-7

124511-67-7 structure

124511-67-7 structure

Name: κ-Bungarotoxin
Chemical Name: κ-Bungarotoxin
CAS Number: 124511-67-7
Molecular Formula: C₃₀₃H₄₇₅N₉₁O₉₇S₁₀
Molecular Weight: 7265.22
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2024-04-08 19:05:04
Modify Date: 2025-09-22 19:23:55
κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC50 of 2.30 nM[1].

Name	κ-Bungarotoxin

Description	κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC50 of 2.30 nM[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	IC50: 2.30 nM (recombinantly expressed in P. pastoris against α3β2)[1]
References	[1]. Grant GA, et al. Differential roles for disulfide bonds in the structural integrity and biological activity of kappa-Bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist. Biochemistry. 1998 Sep 1;37(35):12166-71.

Molecular Formula	C₃₀₃H₄₇₅N₉₁O₉₇S₁₀
Molecular Weight	7265.22

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