1496617-64-1

1496617-64-1 structure

Name: α-Conotoxin TxID
Chemical Name: α-Conotoxin TxID
CAS Number: 1496617-64-1
Molecular Formula: C₅₈H₉₂N₁₈O₁₈S₅
Molecular Weight: 1489.79
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2023-10-27 15:12:45
Modify Date: 2024-04-05 18:38:19
α-Conotoxin TxID is a potent α3β4 nAChR antagonist with an IC50 value of 12.5 nM. α-Conotoxin TxID has weak inhibition activity of closely related α6/α3β4 nAChR (IC50= 94 nM). α-Conotoxin TxID has the potential for novel smoking cessation drug development[1].

Name	α-Conotoxin TxID

Description	α-Conotoxin TxID is a potent α3β4 nAChR antagonist with an IC50 value of 12.5 nM. α-Conotoxin TxID has weak inhibition activity of closely related α6/α3β4 nAChR (IC50= 94 nM). α-Conotoxin TxID has the potential for novel smoking cessation drug development[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	IC50: α3β4 nAChR
References	[1]. Xiaodan Li, et al. α-Conotoxin TxID and [S9K]TxID, α3β4 nAChR Antagonists, Attenuate Expression and Reinstatement of Nicotine-Induced Conditioned Place Preference in Mice. . Mar Drugs. 2020 Dec 16;18(12):646. doi: 10.3390/md18120646.

Molecular Formula	C₅₈H₉₂N₁₈O₁₈S₅
Molecular Weight	1489.79