2923366-36-1

2923366-36-1 structure
2923366-36-1 structure
  • Name: hBChE-IN-2
  • Chemical Name: hBChE-IN-2
  • CAS Number: 2923366-36-1
  • Molecular Formula: C27H36N4O3
  • Molecular Weight: 464.60
  • Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
  • Create Date: 2023-09-23 12:21:49
  • Modify Date: 2024-01-27 18:19:23
  • hBChE-IN-2 (compound 15d) is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. hBChE-IN-2 has neuroprotection activities[1].

Name hBChE-IN-2
Description hBChE-IN-2 (compound 15d) is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. hBChE-IN-2 has neuroprotection activities[1].
Related Catalog
Target

hBCHE:0.67 μM (IC50)

hCB2-R:0.78 μM (IC50)

References

[1]. Philipp Spatz, et al. Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model. J Med Chem. 2023 May 11;66(9):6414-6435.  

Molecular Formula C27H36N4O3
Molecular Weight 464.60