Name | BACE1-IN-13 |
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Description | BACE1-IN-13 (Compound 36) is an orally active BACE1 inhibitor with an IC50 value of 2.9 nM. BACE1-IN-13 is highly potent in hAβ42 cell (IC50 = 1.3 nM). BACE1-IN-13 has cardiovascularly safty and elicits sustained Aβ42 reduction in mouse and dog animal models[1]. |
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Related Catalog | |
Target |
IC50: 1.3 nM (hAβ42 cell)[1]. |
References |
Molecular Formula | C20H17FN8O2 |
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Molecular Weight | 420.40 |