1420777-30-5

1420777-30-5 structure

Name: Microgrewiapine A
Chemical Name: Microgrewiapine A
CAS Number: 1420777-30-5
Molecular Formula: C₁₇H₂₉NO
Molecular Weight: 263.42
Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
Create Date: 2022-10-06 09:30:22
Modify Date: 2024-04-08 13:07:06
Microgrewiapine A is an antagonist of nAChR. Microgrewiapine A inhibits hα4β2 and hα3β4 activity with 60% and 70% inhibition, respectively. Microgrewiapine A has selective cytotoxic against HT-29 human colon cancer cells with an IC50 of 6.8 μM[1].

Name	Microgrewiapine A

Description	Microgrewiapine A is an antagonist of nAChR. Microgrewiapine A inhibits hα4β2 and hα3β4 activity with 60% and 70% inhibition, respectively. Microgrewiapine A has selective cytotoxic against HT-29 human colon cancer cells with an IC50 of 6.8 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. Still PC, et al. Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities. J Nat Prod. 2013 Feb 22;76(2):243-9.

Molecular Formula	C₁₇H₂₉NO
Molecular Weight	263.42