515866-67-8

515866-67-8 structure

Name: 5-bromo-N-(2-morpholinoethyl)nicotinamide
Chemical Name: 5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide
CAS Number: 515866-67-8
Molecular Formula: C₁₂H₁₆BrN₃O₂
Molecular Weight: 314.178
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2022-08-16 17:54:08
Modify Date: 2024-04-05 21:52:38
WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide derivative that inhibits monoamine oxidase (Monoamine Oxidase). WAY-620147 inhibits MAO-A and MAO-B with IC50s of 26 μM and 55 μM, respectively[1].

Name	5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide
Synonyms	3-Pyridinecarboxamide, 5-bromo-N-[2-(4-morpholinyl)ethyl]- 5-bromo-N-[2-(morpholin-4-yl)ethyl]pyridine-3-carboxamide MFCD04225865 5-Bromo-N-[2-(4-morpholinyl)ethyl]nicotinamide

Description	WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide derivative that inhibits monoamine oxidase (Monoamine Oxidase). WAY-620147 inhibits MAO-A and MAO-B with IC50s of 26 μM and 55 μM, respectively[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	IC50: 26 μM (MAO-A), 55 μM (MAO-B)[1]
References	[1]. Shi L, et al. Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors. Bioorg Med Chem. 2010 Feb 15;18(4):1659-64.