2084059-97-0
2084059-97-0 structure
- Name: BI-8668
- Chemical Name: BI-8668
- CAS Number: 2084059-97-0
- Molecular Formula: C23H32Cl2N8O2
- Molecular Weight: 523.463
- Create Date: 2022-07-01 23:34:47
- Modify Date: 2024-04-08 06:36:18
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BI-8668 (BI 8668) is a highly potent and selective epithelial sodium channel (ENaC) inhibitor, inhibits Na+ current with IC50 of 17 nM (Ussing chamber assay);BI-8668 inhibits ENaC-mediated water permeability through cell monolayers of the cell line M-1 (M-1 cells: mouse kidney tubules cells) with 81% inhibition at 3 uM.
| Name | BI-8668 |
|---|
| Description | BI-8668 (BI 8668) is a highly potent and selective epithelial sodium channel (ENaC) inhibitor, inhibits Na+ current with IC50 of 17 nM (Ussing chamber assay);BI-8668 inhibits ENaC-mediated water permeability through cell monolayers of the cell line M-1 (M-1 cells: mouse kidney tubules cells) with 81% inhibition at 3 uM. |
|---|
| Molecular Formula | C23H32Cl2N8O2 |
|---|---|
| Molecular Weight | 523.463 |