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2237953-19-2

2237953-19-2 structure
2237953-19-2 structure
  • Name: PI3Ka-IN-5
  • Chemical Name: PI3Ka-IN-5
  • CAS Number: 2237953-19-2
  • Molecular Formula: C30H35N9O5
  • Molecular Weight: 601.66
  • Create Date: 2022-05-24 21:39:20
  • Modify Date: 2025-08-26 14:11:27
  • PI3Ka-IN-5 (compound 6 ab) is a potent PI3Kα/mTOR inhibitor, with an IC50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer[1].

Name PI3Ka-IN-5
Description PI3Ka-IN-5 (compound 6 ab) is a potent PI3Kα/mTOR inhibitor, with an IC50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer[1].
Related Catalog
Target

PI3Kα:0.7 nM (IC50)

mTOR:3.3 nM (IC50)

References

[1]. Wu CF, et, al. Synthesis and bioevaluation of diaryl urea derivatives as potential antitumor agents for the treatment of human colorectal cancer. Eur J Med Chem. 2022 Feb 5;229:114055.

Molecular Formula C30H35N9O5
Molecular Weight 601.66
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