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2641059-19-8

2641059-19-8 structure
2641059-19-8 structure
  • Name: LRRK2-IN-2
  • Chemical Name: LRRK2-IN-2
  • CAS Number: 2641059-19-8
  • Molecular Formula: C23H23Cl2F3N6O2
  • Molecular Weight: 543.37
  • Create Date: 2022-05-24 19:22:28
  • Modify Date: 2024-01-13 23:57:18
  • LRRK2-IN-2 (compoubd 22) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of <0.6 nM. LRRK2-IN-2 can be used for the research of Parkinson's disease[1].
Name LRRK2-IN-2
Description LRRK2-IN-2 (compoubd 22) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of <0.6 nM. LRRK2-IN-2 can be used for the research of Parkinson's disease[1].
Related Catalog
Target

IC50: <0.6 nM (LRRK2)[1]

References

[1]. Keylor MH, et, al. Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. J Med Chem. 2022 Jan 13;65(1):838-856.
Molecular Formula C23H23Cl2F3N6O2
Molecular Weight 543.37
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title: CAS No. 2641059-19-8 | Chemsrc address: https://www.chemsrc.com/en/baike/1705427.html

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