Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AGI-12026
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: AGI-12026
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1446501-77-4

1446501-77-4 structure

1446501-77-4 structure

Name: AGI-12026
Chemical Name: AGI-12026
CAS Number: 1446501-77-4
Molecular Formula: C₁₈H₁₅F₆N₇
Molecular Weight: 443.35
Create Date: 2022-05-21 14:16:44
Modify Date: 2025-08-25 13:33:07
AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma[1].

Name	AGI-12026

Description	AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH) Research Areas >> Neurological Disease
References	[1]. Konteatis Z, et al. Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma. ACS Med Chem Lett. 2020;11(2):101-107.

Molecular Formula	C₁₈H₁₅F₆N₇
Molecular Weight	443.35

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