71636-61-8

71636-61-8 structure

Name	9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Synonyms	6-Chlor-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin 8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine C16H16ClNO2 1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl 6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol MFCD00153782

Description	SKF 81297 is a potent and selective dopamine D1 receptor agonist[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D1 Receptor
References	[1]. Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235(1):143-7. [2]. Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	22-26-36
RIDADR	NONH for all modes of transport

67287-38-1

71636-61-8

Literature: Journal of Medicinal Chemistry, , vol. 23, # 9 p. 973 - 975

96-09-3

71636-61-8

Literature: Journal of Medicinal Chemistry, , vol. 23, # 9 p. 973 - 975

67287-37-0

71636-61-8

Literature: Journal of Medicinal Chemistry, , vol. 23, # 9 p. 973 - 975

67287-36-9

71636-61-8

Literature: Journal of Medicinal Chemistry, , vol. 23, # 9 p. 973 - 975

7537-07-7

71636-61-8

Literature: Journal of Medicinal Chemistry, , vol. 23, # 9 p. 973 - 975