708-79-2
708-79-2 structure
- Name: 1-Methyluric acid
- Chemical Name: 1-methyluric acid
- CAS Number: 708-79-2
- Molecular Formula: C6H6N4O3
- Molecular Weight: 182.13700
- Catalog: Biochemical Nucleoside drugs Nucleotides and their analogues
- Create Date: 2018-11-26 09:46:57
- Modify Date: 2024-01-10 18:53:52
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1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.
| Name | 1-methyluric acid |
|---|---|
| Synonyms |
1-methyl-8-oxyxanthine
1-Methyluric acid 1-Methylurate 1MUA 1-methyl-7,9-dihydro-3H-purine-2,6,8-trione 1-Methyl-2,6,8-trihydroxypurine 1-Methyl-harnsaeure |
| Description | 1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vivo | Perfusion of the urinary bladder with 1-Methyl uric acid solution shows an increase in the serum total cholesterol level, true triglyceride level, glucose level and insulin level on comparison with perfusion of the urinary bladder with distilled water[1]. |
| Animal Admin | Rats[1] Adult albino rats of Wistar strain of either sex weighing 200-300 g rats are used for the present study. Thirty albino rats are divided into three groups of ten each. Group I serves as the control group perfused with distilled water. Following cannulation, the bladder is perfused with distilled water. Group II serves as the uric acid perfused group. Group III serves as the 1-Methyl uric acid perfused group. The animals of this group are treated in a similar way as those of control group (Group I) except that the bladder is perfused with the aqueous solution of 1-Methyl uric acid (0.0024 g/100 mL) instead of distilled water[1]. |
| References |
| Density | 1.73g/cm3 |
|---|---|
| Boiling Point | 315.51°C (rough estimate) |
| Melting Point | >325ºC |
| Molecular Formula | C6H6N4O3 |
| Molecular Weight | 182.13700 |
| Exact Mass | 182.04400 |
| PSA | 103.51000 |
| Index of Refraction | 1.695 |
| Storage condition | Refrigerator |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
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708-79-2 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 24, p. 1109 - 1116 |
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| Literature: Justus Liebigs Annalen der Chemie, , vol. 441, p. 209 |
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| Literature: Biological and Pharmaceutical Bulletin, , vol. 18, # 1 p. 75 - 81 |
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| Literature: Justus Liebigs Annalen der Chemie, , vol. 413, p. 133 |
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| Literature: Justus Liebigs Annalen der Chemie, , vol. 413, p. 133 |
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| Literature: Justus Liebigs Annalen der Chemie, , vol. 515, p. 201,250 |
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| Literature: Justus Liebigs Annalen der Chemie, , vol. 515, p. 201,250 |
| Precursor 7 | |
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| DownStream 2 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |