Top Suppliers:I want be here
Related CAS#:
110-60-1 1173023-66-9
333-93-7 5699-41-2
13285-10-4 26148-06-1
39772-63-9 79747-54-9
287100-61-2 60422-23-3
2378507-16-3 2378501-35-8
2377035-99-7 2377030-96-9
2377031-21-3 2377031-60-0
2377035-87-3 2228663-50-9
2410944-64-6 2411241-08-0

110-60-1

110-60-1 structure
110-60-1 structure
Name putrescine
Synonyms 1,4-DIAMINOBUTAN
butane-1.4-diamine
Tetramethylenediamine
1,4-Butanediamine
1,4-butylenediamine
Putrescine, free base
Butan-1,4-diamin
Butane-1,4-diamine
putrescine
EINECS 203-782-3
MFCD00008235
1,4-Diaminobutane
Description 1,4-Butanediamine is an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). 1,4-Butanediamine is an important source of GABA.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 1,4-Butanediamine (Putrescine) is an important source of GABA in the postnatal rat subventricular zone. GABA synthesis from an alternative pathway uses 1,4-Butanediamine as a precursor.
References

[1]. Hauschild MZ. Putrescine (1,4-diaminobutane) as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). Ecotoxicol Environ Saf. 1993 Oct;26(2):228-47.

[2]. Sequerra EB, et al. Putrescine as an important source of GABA in the postnatal rat subventricular zone. Neuroscience. 2007 May 11;146(2):489-93.
Density 0.9±0.1 g/cm3
Boiling Point 159.0±8.0 °C at 760 mmHg
Melting Point 27 °C
Molecular Formula C4H12N2
Molecular Weight 88.151
Flash Point 51.7±0.0 °C
Exact Mass 88.100044
PSA 52.04000
LogP -0.72
Vapour Pressure 2.6±0.3 mmHg at 25°C
Index of Refraction 1.455
Stability Stable. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents. Flammable.
Water Solubility cell culture medium: 0.16 mg/mL

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EJ6800000
CHEMICAL NAME :
1,4-Butanediamine
CAS REGISTRY NUMBER :
110-60-1
BEILSTEIN REFERENCE NO. :
0605282
LAST UPDATED :
199712
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C4-H12-N2
MOLECULAR WEIGHT :
88.18
WISWESSER LINE NOTATION :
Z4Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
463 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Sense Organs and Special Senses (Eye) - ptosis Kidney, Ureter, Bladder - other changes in urine composition
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1750 mg/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity Vascular - BP lowering not characterized in autonomic section
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1576 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Kidney, Ureter, Bladder - other changes in urine composition Skin and Appendages - dermatitis, other (after systemic exposure)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Rectal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
314 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - other effects to embryo Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - mouse Liver
DOSE/DURATION :
20 mmol/L
REFERENCE :
AMOKAG Acta Medicia Okayama. (Okayama Univ. Medical School, Okayama, Japan) V.27 1973- Volume(issue)/page/year: 33,149,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4958 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 3 (estimated) No. of Female Employees: 3 (estimated)
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger
Hazard Statements H226-H302-H311-H314-H330
Precautionary Statements P210-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P370 + P378
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive
Risk Phrases R20/21/22;R34
Safety Phrases S16-S26-S36/37/39-S45
RIDADR UN 2928 6.1/PG 2
WGK Germany 3
RTECS EJ6800000
Packaging Group II
Hazard Class 8
HS Code 2921290000
HS Code 2921290000
Summary 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:110-60-1 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 110-60-1 | Chemsrc address: https://www.chemsrc.com/en/baike/166443.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved