298-93-1

298-93-1 structure

Name: Thiazolyl Blue
Chemical Name: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
CAS Number: 298-93-1
Molecular Formula: C₁₈H₁₆BrN₅S
Molecular Weight: 414.322
Catalog: Chemical reagent Organic reagent Azo, diazonium compound
Create Date: 2018-02-04 08:00:00
Modify Date: 2024-01-02 18:39:32
MTT is a colorimetric agent widely used to measure cell proliferation. MTT is reduced from yellow color to purple formazan in living cells.

Name	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
Synonyms	3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide ThiazolylBlue(Mtt) MttA.R. 2H-Tetrazolium, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-, bromide (1:1) 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium Bromide 3-(4,5-Dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2H-tetrazol-3-ium bromide Methylthiazoletetrazolium bromide Thiazolyl Blue 2H-tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (1:1) 2-(4,5-Dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide MFCD00011964 EINECS 206-069-5 THIAZOLE BLUE Thiazolyl blue tetrazolium bromide (MTT) thiazolyl blue tetrazolium bromide mmttetrazolium 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyl-2H-Tetrazolium Bromide MTT

Description	MTT is a colorimetric agent widely used to measure cell proliferation. MTT is reduced from yellow color to purple formazan in living cells.
Related Catalog	Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others
In Vitro	MTT is used in conjunction with rhodamine B to measure mitochondrial membrane potential. MTT-formazan is generated in mitochondria acts as a fluorescence quencher for rhodamine that distributes across membranes of viable cells according to membrane potential. In the absence of mPMS, cellular reduction of MTT is strong. MTT is membrane-impermeable when incorporated into large unilamellar liposomes, and therefore it is taken up by cells via endocytosis[1].
References	[1]. Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52.

CHEMICAL NAME :: 2H-Tetrazolium, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-, bromide

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 68,107,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1328 No. of Facilities: 93 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1106 (estimated) No. of Female Employees: 985 (estimated)

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H315-H319-H335-H341
Precautionary Statements	P261-P281-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R46
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XF8060000
HS Code	29341000

HS Code	29341000